Antisocial behaviour poses a major burden for society as it often involves acts of breaking the law, violence and aggression towards others. Nonetheless the diverse roots of the antisocial behaviour make it challenging to untangle its causes. Understanding how genetic predispositions interact with environmental factors (GxE interaction) and contribute to antisocial behaviours has great potential for advancing the understanding of the development of this condition. This article aims thus to critically review the strongest candidates GxE interaction, illustrating the initial findings and exploring subsequent evidences.

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